The objectives of this work are to investigate the status of implementation of quality initiatives by manufacturing firms in Madhya Pradesh, India, and to compare large and small-medium scale industries. Very few researchers have attempted to compare large scale and small-medium scale firms in order to know the extent of implementation of quality initiatives for a state like Madhya Pradesh. In this study, the survey questionnaire method was used for the collection of data. Nine quality initiatives were selected for the study. The obtained data are grouped into two groups, viz., (i) large scale firms, and (ii) small-medium scale firms. Descriptive and inferential statistics are used for analysis and the results are presented. Hypothesis testing was used to investigate for any significant difference between the two groups of firms in implementing each quality initiative. Results from inferential statistics reveal that there is a significant difference in the implementation of quality initiatives in large and small-medium scale industries. The findings of the present work will guide firms to identify areas where improvement is required at each quality initiative level. The study will help small-medium scale firms in the Madhya Pradesh state of India to conduct training programs in the areas of relevant quality initiatives for improving their quality of products.